実施概要

プログラム

開会の挨拶

横山美夏
京都大学欧州拠点所長

Dr. Klaus Rümmele
Head of International Affairs Business Unit, KIT

パラレルダイアログ

Dialogue1

岡村亮輔【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 医学部附属病院 消化管外科 助教

Dr. Johannes Betge (DKFZ)
Translational Gastrointestinal Oncology and Preclinical Models Junior Clinical Cooperation Unit
DKFZ

Dr. Jörg Leupold
Department of Experimental Surgery, Cancer Metastasis, Heidelberg University

Dr. Nitin Patil
Department of Experimental Surgery, Cancer Metastasis, Heidelberg University

Prof. Dr. Anne-Christin Hauschild
Department of Medical Informatics University Medical Center Göttingen, University of Göttingen

消化器癌に対するバイオマーカーを用いた個別化外科治療
Background/Motivation:
Despite the recent development of surgical technology, we unfortunately see postoperative disease recurrence in many of advanced GI cancer cases. We surgeons should know the limits of surgical strategy for controlling tumor spread. How should current precision oncology, such as molecular profiling and biomarker-driven cancer therapy, be combined with surgery to improve GI cancer patients’ outcomes?

Dialogue2

田中智大【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 工学研究科 社会基盤工学専攻水工学講座 助教

Dr. Simon Schaub
Institute of Political Science, Heidelberg University

Dr. Guyen Battuvshin
Institute of Geography, Heidelberg University

Prof. Dr. Martin Sauter
Geoscience Center, University of Goettingen

2050年の水文学研究
Background/Motivation:
Water sciences, such as hydrology, climatology, limnology, oceanology, coastal engineering, etc., pay the ever-strongest attention to climate change (CC) and its impact assessments. In 1990s and 2000s, CC research in hydrology was simply translating future projected rainfall to the resultant water cycle. Now, this topic became further more sophisticated, including more detailed hydraulic analysis such as inundation, landslides and their translation into economic impacts. The urgent needs of society for climate change adaptation accelerated such studies during this short period. In 2050, when climate change more explicitly emerges, how will or should our hydrological research, especially for CC assessments/adaptation/mitigation go? I would like to discuss the future of hydrology research: more social sciences associated, climate change validation, hydrological modelling, hydrological observation, etc.

Dialogue3

井上浩輔【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 医学研究科 社会健康医学系専攻国際保健学講座社会疫学 助教

PD Dr. Volker Winkler
Heidelberg Institute of Global Health, Epidemiology of Transition, Heidelberg University Hospital

Junior-Prof. Dr. Tim Mathes
Department of Medical Statistics at the University Medical Center Göttingen

Pelin Ünal
Genomic Epidemiology Group
DKFZ

Tomislav Vlaski
Division of Clinical Epidemiology and Aging
Research
DKFZ

2030年の医療科学における疫学・統計学の役割
Background/Motivation:
Given the recent rapid advancement of computer science, big data, and machine learning as well as increasing concern over social disparity, what knowledge and skillsets would be appreciated in future science and medicine? What can we do to improve health towards precision medicine (in real meaning)?

Dialogue4

白石晃將【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 農学研究科 応用生命科学専攻応用微生物学講座 助教

Gideon Bergheim
Centre for Organismal Studies (COS) Heidelberg

Dr.Islam Khattab
Karlsruhe Institute of Technology, Institute for Biological Interfaces

Noemi Flubacher
Botanical Institute, KIT

Prof. Dr. Tobias Erb
Max Planck Institute for Terrestrial Microbiology, Marburg, Germany

植物-微生物相互作用に関する知見をどのように世界レベルでの政策対話に統合できるか／すべきか
Background/Motivation:
Plant-microbe interaction is a complex, dynamic and continuous process. It has been shown to support plant growth and increase host resistance to pathogens, and the rhizosphere, the underground part, has been the center of the research. Recently, the phyllosphere, the plant leaf surface, has attracted many scientists and phyllosphere microbes have been recognized as important players. New insights have been put into practical applications such as biostimulants for crop yield promotion and plant protection from pathogens. Looking at the accumulating evidence from the perspective of scientific advice for policy-making, the plant-microbe interaction of the rhizosphere has been discussed in international policy dialogues, whereas that of the phyllosphere is stuck in dialogues among researchers. Through some international expert communities, we have started to share new knowledge on phyllosphere microbiology with the expectation to bring the discussion to international policy dialogues for food security and environmental protection.

Dialogue5

磯部昌憲【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 医学部附属病院 精神科神経科 助教

Dr. Jerome Foo
Dept. Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University

Kelly Amal Dhru, LL.M.
Faculty of Law, Universität Hamburg

Konrad Waschkies
Department of Psychiatry and Psychotherapy University of Göttingen

Tuyu Zheng
Department of Pediatric Neuro-Oncology KITZ

人類はどうなるのか/どうなりえるのか/どうあるべきか
Background/Motivation:
Currently, various state-of-art technics to enhance intellectual ability, such as decoded neurofeedback, have been developed and are now close to be implemented in the clinical field. Careful discussion in advance would be desirable from multiple perspectives as follows; how far the expansion of physical and cognitive functions should go, how far it should be allowed to go, and what kind of common understanding and restrictions are necessary when this expansion proceeds. For example, restrictions have been placed on human cloning, but what extent do such restrictions need to be extended to enhancement of our physical/mental activities? What remains as our individuality? I would like to discuss these issues with people from various fields including those who specialize in bioethics, law, and those who are researching the improvement of cognitive function and recovery of physical function.

Dialogue6

江口佳那【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 医学研究科 リアルワールドデータ研究開発講座 特定助教

Dr. Nicolai Spicher
Department of Medical Informatics, University Medical Center Göttingen

Dr. Sebastian Herberger
Interdisciplinary Center of Sleep Medicine Charité-Universitätsmedizin, Berlin

高齢社会におけるITリテラシー格差を医療技術はどう克服すべきか？
Background/Motivation:
Aging and health now become a worldwide problem. On the basis of WHO’s fact sheets [ref1], the proportion of the world’s population over 60 years will become 22%, while 80% of them will be living in low- or middle-income countries. These situations may cause an ever-greater digital literacy gap, which may even affect access to healthcare or medical service.
At this moment, our study has already faced the digital literacy gap-induced problems in collecting side-effect reports from patients undergoing cancer pharmacotherapy: we confirmed that the use of smartphone applications may become a big hurdle for aged Japanese people. In this dialogue, I would like to first exchange the current situation in Germany and Japan related to the issues surrounding healthcare induced by the digital literacy gap. Then discuss possible issues induced by the digital literacy gap in the future and how we can/should overcome the vicious circle of technology development and the digital literacy gap.
[ref1] https://www.who.int/news-room/fact-sheets/detail/ageing-and-health

Dialogue7

飯間麻美【 L-INSIGHT fellow 】
京都大学 L-INSIGHT / 医学部附属病院 先端医療研究開発機構・放射線診断科 助教

A/Prof. Dr. Dimitrios Karampinos
Experimental Magnetic Resonance Imaging School of Medicine & Munich Institute of Biomedical Engineering Technical University of Munich

PD Dr. Sebastian Bickelhaupt
Institute for Radiology
University Hospital Erlangen

Dr. Felix Kurz
Division of Radiology
DKFZ

腫瘍イメージングにおけるマクロスケールとミクロスケールの橋渡し
Background/Motivation:
We will aim to establish a trans-scale imaging method that connects a whole body, tissue, and cellular scales using MRI etc, especially diffusion MRI, which can evaluate the movement of water molecules in vivo. In the diagnosis of cancer, it is important to understand the phenomenon and elucidate the mechanism by traversing various scales, such as the tumor microenvironment and micrometastases that may exist throughout the body. However, the understanding of the principles that will lead to the elucidation of new pathological conditions at the microscopic level involving elemental interactions in biomolecules and cells, and at the meso- and macro-level involving tissues and organs, has not yet been fully developed.
The current MRI has difficulty in measuring and evaluating the micro level, especially in terms of resolution, and thus we will aim to develop this method further to establish trans-scale imaging to visualize cancer characteristics on a longitudinal scale and exploit them for cancer diagnosis and prognosis prediction.

全体討論

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コメンテーター

Prof. Dr. Thomas Kneib
Dean of research at the Faculty of Business and Economic Sciences, University of Goettingen

Prof. TANAKA Motomu
Institute for Physical Chemistry, Heidelberg University

河野泰之
京都大学 国際戦略本部長・副学長

閉会の挨拶

Nicole Dorn
International Relations Division, Department Study Abroad, Exchange Programmes, International Cooperation

赤松 明彦
京都大学 次世代研究創成ユニット長/プログラムマネージャー

主催

ハイデルベルク大学
カールスルーエ工科大学
ゲッチンゲン大学
京都大学